We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Colorectal, breast and prostate cancers displayed moderate cytoplasmic staining. Remaining malignant cells were generally weakly stained or negative.
GENE INFORMATION
Gene name
SLMAP (HGNC Symbol)
Synonyms
KIAA1601, SLAP
Description
Sarcolemma associated protein (HGNC Symbol)
Entrez gene summary
This gene encodes a component of a conserved striatin-interacting phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
B7Z964 [Direct mapping] Sarcolemmal membrane-associated protein; cDNA FLJ60222, highly similar to Homo sapiens sarcolemma associated protein (SLMAP), mRNA; cDNA, FLJ79335, highly similar to Homo sapiens sarcolemma associated protein (SLMAP), mRNA
Show all
Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014)