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RPL9

GENERAL INFORMATION

Gene name

 RPL9

Gene description

 Ribosomal protein L9

Protein class

 Plasma proteins
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Caution, Splice and/or transcript discrepancy exists. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA003372
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA003372

GENE INFORMATION

Gene name

 RPL9 (HGNC Symbol)

Synonyms

 L9

Description

 Ribosomal protein L9 (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 4

Cytoband

 p14

Chromosome location (bp)

 39454124 - 39458948

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163682 (version 83.38)

Entrez gene

 6133

UniProt

 P32969 (UniProt - Evidence at protein level)

neXtProt

 NX_P32969

Antibodypedia

 RPL9 antibodies

PROTEIN BROWSER
RPL9-001
RPL9-002
RPL9-007
RPL9-009
RPL9-011
RPL9-012

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPL9-001
ENSP00000346022
ENST00000295955
P32969 [Direct mapping]
60S ribosomal protein L9
Q53Z07 [Target identity:100%; Query identity:100%]
60S ribosomal protein L9; NPC-A-16; Ribosomal protein L9; Ribosomal protein L9 isoform; Ribosomal protein L9, isoform CRA_b; cDNA, FLJ92535, Homo sapiens ribosomal protein L9 (RPL9), mRNA
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Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019843 [rRNA binding]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
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 192 aa
21.9 kDa 		No 0
RPL9-002
ENSP00000400467
ENST00000449470
P32969 [Direct mapping]
60S ribosomal protein L9
Q53Z07 [Target identity:100%; Query identity:100%]
60S ribosomal protein L9; NPC-A-16; Ribosomal protein L9; Ribosomal protein L9 isoform; Ribosomal protein L9, isoform CRA_b; cDNA, FLJ92535, Homo sapiens ribosomal protein L9 (RPL9), mRNA
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Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019843 [rRNA binding]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
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 192 aa
21.9 kDa 		No 0
RPL9-007
ENSP00000425250
ENST00000508595
H0Y9V9 [Direct mapping]
60S ribosomal protein L9
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0019843 [rRNA binding]
Show all
 189 aa
21.5 kDa 		No 0
RPL9-009
ENSP00000422191
ENST00000504470
E7ESE0 [Direct mapping]
60S ribosomal protein L9
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0019843 [rRNA binding]
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 166 aa
18.9 kDa 		No 0
RPL9-011
ENSP00000421872
ENST00000503040
D6RAN4 [Direct mapping]
60S ribosomal protein L9
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0019843 [rRNA binding]
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 182 aa
20.9 kDa 		No 0
RPL9-012
ENSP00000424796
ENST00000506581
H0Y9R4 [Direct mapping]
60S ribosomal protein L9
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0019843 [rRNA binding]
Show all
 91 aa
10 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.