Expression of SMIM14 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

SMIM14

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SMIM14
Gene description	Small integral membrane protein 14
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (Daudi)
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in all tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA051299
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in head and neck cancer (favourable), renal cancer (favourable), endometrial cancer (favourable) and liver cancer (favourable).
Head and neck cancer p<0.001 Renal cancer p<0.001 Endometrial cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA051299

GENE INFORMATION
Gene name	SMIM14 (HGNC Symbol)
Synonyms	C4orf34, FLJ13289
Description	Small integral membrane protein 14 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	p14
Chromosome location (bp)	39546330 - 39639090
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163683 (version 83.38)
Entrez gene	201895
UniProt	Q96QK8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96QK8
Antibodypedia	SMIM14 antibodies

PROTEIN BROWSER

SMIM14-001	SMIM14-002	SMIM14-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SMIM14-001 ENSP00000295958 ENST00000295958	Q96QK8 [Direct mapping] Small integral membrane protein 14 A0A024R9S4 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] Show all	99 aa 10.7 kDa	No	1
SMIM14-002 ENSP00000422904 ENST00000505729	D6R9U3 [Direct mapping] Small integral membrane protein 14 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	89 aa 9.7 kDa	No	1
SMIM14-004 ENSP00000421087 ENST00000511809	D6RGZ0 [Direct mapping] Small integral membrane protein 14 Show all	Predicted intracellular proteins Show all		54 aa 6.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.