Expression of TCF23 in cancer - Summary - The Human Protein Atlas

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TCF23

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	TCF23
Gene description	Transcription factor 23
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enriched (THP-1)
HPA (normal tissue):	Tissue enhanced (endometrium, ovary, smooth muscle)

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	TCF23 (HGNC Symbol)
Synonyms	bHLHa24, OUT
Description	Transcription factor 23 (HGNC Symbol)
Entrez gene summary	The gene encodes a member of the basic helix-loop-helix transcription factor family. Studies of the orthologous gene in mouse have shown the encoded protein does not bind DNA but may negatively regulate other basic helix-loop-helix factors via the formation of a functionally inactive heterodimeric complex. [provided by RefSeq, May 2010]
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	27149004 - 27156974
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000163792 (version 83.38)
Entrez gene	150921
UniProt	Q7RTU1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7RTU1
Antibodypedia	TCF23 antibodies

PROTEIN BROWSER

TCF23-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TCF23-001 ENSP00000296096 ENST00000296096	Q7RTU1 [Direct mapping] Transcription factor 23 Show all	Predicted intracellular proteins Transcription factors Basic domains Show all	GO:0005634 [nucleus] GO:0007517 [muscle organ development] GO:0030154 [cell differentiation] GO:0046983 [protein dimerization activity] Show all	214 aa 23.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.