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TGM4

GENERAL INFORMATION

Gene name

 TGM4

Gene description

 Transglutaminase 4

Protein class

 Cancer-related genes
Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (prostate)
GTEx:Tissue enriched (prostate)
FANTOM5:Tissue enriched (prostate)

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression in prostate and skeletal muscle.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA032072 , CAB033571
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (prostate)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (prostate)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (prostate)

GENE INFORMATION

Gene name

 TGM4 (HGNC Symbol)

Synonyms

 TGP

Description

 Transglutaminase 4 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 p21.31

Chromosome location (bp)

 44874608 - 44914990

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163810 (version 83.38)

Entrez gene

 7047

UniProt

 P49221 (UniProt - Evidence at protein level)

neXtProt

 NX_P49221

Antibodypedia

 TGM4 antibodies

PROTEIN BROWSER
TGM4-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TGM4-001
ENSP00000296125
ENST00000296125
P49221 [Direct mapping]
Protein-glutamine gamma-glutamyltransferase 4
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Enzymes
   ENZYME proteins
   Transferases
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003810 [protein-glutamine gamma-glutamyltransferase activity]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0018149 [peptide cross-linking]
GO:0031012 [extracellular matrix]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
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 684 aa
77.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.