Expression of ZMYM6 in cancer - Summary - The Human Protein Atlas

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ZMYM6

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZMYM6
Gene description	Zinc finger, MYM-type 6
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA011004
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PROGNOSTIC SUMMARY
Prognostic marker in breast cancer (favourable).
Breast cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA011004

GENE INFORMATION
Gene name	ZMYM6 (HGNC Symbol)
Synonyms	Buster2, MYM, ZBED7, ZNF198L4, ZNF258
Description	Zinc finger, MYM-type 6 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.3
Chromosome location (bp)	34986165 - 35031968
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163867 (version 83.38)
Entrez gene	9204
UniProt	O95789 (UniProt - Evidence at transcript level)
neXtProt	NX_O95789
Antibodypedia	ZMYM6 antibodies

PROTEIN BROWSER

ZMYM6-001	ZMYM6-002	ZMYM6-005	ZMYM6-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZMYM6-001 ENSP00000349708 ENST00000357182	O95789 [Direct mapping] Zinc finger MYM-type protein 6 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0007010 [cytoskeleton organization] GO:0007275 [multicellular organismal development] GO:0008270 [zinc ion binding] GO:0022604 [regulation of cell morphogenesis] Show all	1325 aa 148.1 kDa	No	0
ZMYM6-002 ENSP00000326695 ENST00000317538	O95789 [Direct mapping] Zinc finger MYM-type protein 6 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0007010 [cytoskeleton organization] GO:0007275 [multicellular organismal development] GO:0008270 [zinc ion binding] GO:0022604 [regulation of cell morphogenesis] Show all	170 aa 18.7 kDa	No	1
ZMYM6-005 ENSP00000362430 ENST00000373333	O95789 [Direct mapping] Zinc finger MYM-type protein 6 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0007010 [cytoskeleton organization] GO:0007275 [multicellular organismal development] GO:0008270 [zinc ion binding] GO:0022604 [regulation of cell morphogenesis] Show all	170 aa 18.7 kDa	No	1
ZMYM6-008 ENSP00000391337 ENST00000415531	X6RCN5 [Direct mapping] Zinc finger MYM-type protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] Show all	208 aa 22.9 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.