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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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RPL39L
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

RPL39L

Gene description

Ribosomal protein L39-like

Protein class

Predicted intracellular proteins
Ribosomal proteins

Predicted localization

Intracellular

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression mainly in testis.

ANTIBODY IHC RELIABILITY

Data reliability
description

Caution, targets protein from more than one gene. Pending external verification.

Reliability score

Approved based on 1 antibody.
HPA047105
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PROGNOSTIC SUMMARY

Prognostic marker in glioma (unfavourable), ovarian cancer (favourable) and endometrial cancer (unfavourable).
Glioma p<0.001
Ovarian cancer p<0.001
Endometrial cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA047105

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Several cases of liver cancers along with a few cases of gliomas showed weak to moderate cytoplasmic positivity. Remaining cancer tissues were negative.

GENE INFORMATION

Gene name

RPL39L (HGNC Symbol)

Synonyms

RPL39L1

Description

Ribosomal protein L39-like (HGNC Symbol)

Entrez gene summary

This gene encodes a protein sharing high sequence similarity with ribosomal protein L39. Although the name of this gene has been referred to as 'ribosomal protein L39' in the public databases, its official name is 'ribosomal protein L39-like'. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q27.3

Chromosome location (bp)

187120948 - 187180908

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163923 (version 83.38)

Entrez gene

116832

UniProt

Q96EH5 (UniProt - Evidence at protein level)

neXtProt

NX_Q96EH5

Antibodypedia

RPL39L antibodies

PROTEIN BROWSER

RPL39L-001
RPL39L-002
RPL39L-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPL39L-001
ENSP00000397240
ENST00000455270
Q96EH5 [Direct mapping]
60S ribosomal protein L39-like
Show all
Ribosomal proteins
Predicted intracellular proteins
Show all
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0007283 [spermatogenesis]
GO:0022625 [cytosolic large ribosomal subunit]
Show all
51 aa
6.3 kDa
No 0
RPL39L-002
ENSP00000296277
ENST00000296277
Q96EH5 [Direct mapping]
60S ribosomal protein L39-like
Show all
Ribosomal proteins
Predicted intracellular proteins
Show all
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0007283 [spermatogenesis]
GO:0022625 [cytosolic large ribosomal subunit]
Show all
51 aa
6.3 kDa
No 0
RPL39L-003
ENSP00000389356
ENST00000433055
Q96EH5 [Direct mapping]
60S ribosomal protein L39-like
Show all
Ribosomal proteins
Predicted intracellular proteins
Show all
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0007283 [spermatogenesis]
GO:0022625 [cytosolic large ribosomal subunit]
Show all
51 aa
6.3 kDa
No 0

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