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ABLIM2

GENERAL INFORMATION

Gene name

 ABLIM2

Gene description

 Actin binding LIM protein family, member 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 11
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Group enriched (SCLC-21H, SiHa, U-2197)
HPA (normal tissue):Tissue enhanced (skeletal muscle, spleen)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Distinct membranous expression in selected tissues, along with cytoplasmic staining in other tissues including skeletal muscle.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

 Uncertain based on 1 antibody.
HPA035808
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA035808

GENE INFORMATION

Gene name

 ABLIM2 (HGNC Symbol)

Synonyms

 KIAA1808

Description

 Actin binding LIM protein family, member 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 4

Cytoband

 p16.1

Chromosome location (bp)

 7965310 - 8158832

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163995 (version 83.38)

Entrez gene

 84448

UniProt

 Q6H8Q1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6H8Q1

Antibodypedia

 ABLIM2 antibodies

PROTEIN BROWSER
«
ABLIM2-001
ABLIM2-002
ABLIM2-003
ABLIM2-004
ABLIM2-005
ABLIM2-006
ABLIM2-009
ABLIM2-010
ABLIM2-016
ABLIM2-201
ABLIM2-202
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ABLIM2-001
ENSP00000384658
ENST00000407564
Q6H8Q1 [Direct mapping]
Actin-binding LIM protein 2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
Show all
 521 aa
58 kDa 		No 0
ABLIM2-002
ENSP00000342813
ENST00000341937
Q6H8Q1 [Direct mapping]
Actin-binding LIM protein 2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
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 611 aa
67.8 kDa 		No 0
ABLIM2-003
ENSP00000354887
ENST00000361737
Q6H8Q1 [Direct mapping]
Actin-binding LIM protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
Show all
 531 aa
59 kDa 		No 0
ABLIM2-004
ENSP00000355003
ENST00000361581
Q6H8Q1 [Direct mapping]
Actin-binding LIM protein 2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
Show all
 572 aa
63.6 kDa 		No 0
ABLIM2-005
ENSP00000423661
ENST00000514025
Q6H8Q1 [Direct mapping]
Actin-binding LIM protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
Show all
 346 aa
39 kDa 		No 0
ABLIM2-006
ENSP00000421283
ENST00000505872
Q6H8Q1 [Direct mapping]
Actin-binding LIM protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
Show all
 559 aa
62 kDa 		No 0
ABLIM2-009
ENSP00000389410
ENST00000428004
Q6H8Q1 [Direct mapping]
Actin-binding LIM protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
Show all
 470 aa
51.7 kDa 		No 0
ABLIM2-010
ENSP00000421718
ENST00000510277
D6RAL0 [Direct mapping]
Actin-binding LIM protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0030036 [actin cytoskeleton organization]
Show all
 305 aa
33.6 kDa 		No 0
ABLIM2-016
ENSP00000393511
ENST00000447017
Q6H8Q1 [Direct mapping]
Actin-binding LIM protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0015629 [actin cytoskeleton]
GO:0030016 [myofibril]
GO:0030036 [actin cytoskeleton organization]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
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 645 aa
71.5 kDa 		No 0
ABLIM2-201
ENSP00000317020
ENST00000318888
A0A0A0MR40 [Direct mapping]
Actin-binding LIM protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0008270 [zinc ion binding]
GO:0030036 [actin cytoskeleton organization]
Show all
 644 aa
71.3 kDa 		No 0
ABLIM2-202
ENSP00000441255
ENST00000545242
F5GYR0 [Direct mapping]
Actin-binding LIM protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0008270 [zinc ion binding]
GO:0030036 [actin cytoskeleton organization]
Show all
 646 aa
71.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.