Expression of TMEM144 in cancer - Summary - The Human Protein Atlas

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TMEM144

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM144
Gene description	Transmembrane protein 144
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	12
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (BEWO)
HPA (normal tissue):	Tissue enhanced (cerebral cortex)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA043767
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable) and pancreatic cancer (unfavourable).
Endometrial cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043767

GENE INFORMATION
Gene name	TMEM144 (HGNC Symbol)
Synonyms	FLJ11155
Description	Transmembrane protein 144 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	q32.1
Chromosome location (bp)	158201604 - 158255411
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000164124 (version 83.38)
Entrez gene	55314
UniProt	Q7Z5S9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z5S9
Antibodypedia	TMEM144 antibodies

PROTEIN BROWSER

TMEM144-001	TMEM144-002	TMEM144-003	TMEM144-006	TMEM144-007	TMEM144-008	TMEM144-009	TMEM144-010	TMEM144-012	TMEM144-013	TMEM144-014	TMEM144-016

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM144-001 ENSP00000296529 ENST00000296529	Q7Z5S9 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	345 aa 37.7 kDa	No	9
TMEM144-002 ENSP00000426211 ENST00000514558	Q7Z5S9 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	169 aa 18.3 kDa	No	4
TMEM144-003 ENSP00000425815 ENST00000509278	D6RIX5 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	73 aa 8.2 kDa	No	2
TMEM144-006 ENSP00000422255 ENST00000511038		Predicted intracellular proteins Show all		10 aa 1.1 kDa	No	0
TMEM144-007 ENSP00000421289 ENST00000505189	D6RAX5 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	87 aa 9.5 kDa	No	3
TMEM144-008 ENSP00000425266 ENST00000505049	D6RDN8 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	77 aa 8.5 kDa	No	2
TMEM144-009 ENSP00000422297 ENST00000508243	D6RCA2 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	167 aa 18.1 kDa	No	4
TMEM144-010 ENSP00000422082 ENST00000504569	D6R9I0 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	137 aa 14.7 kDa	No	4
TMEM144-012 ENSP00000420990 ENST00000503200	D6RDF9 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	110 aa 11.8 kDa	No	4
TMEM144-013 ENSP00000422899 ENST00000514971	D6R9U5 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	91 aa 9.9 kDa	No	3
TMEM144-014 ENSP00000425907 ENST00000502698	D6RDN8 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	77 aa 8.5 kDa	No	2
TMEM144-016 ENSP00000424659 ENST00000512481	D6RAX5 [Direct mapping] Transmembrane protein 144 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	87 aa 9.5 kDa	No	3

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The Human Protein Atlas

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