Expression of FAM170A in cancer - Summary - The Human Protein Atlas

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FAM170A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM170A
Gene description	Family with sequence similarity 170, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear and cytoplasmic expression in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 3 antibodies. HPA037900 , HPA037901 , HPA037902
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA037900	HPA037901	HPA037902

GENE INFORMATION
Gene name	FAM170A
Synonyms
Description	Family with sequence similarity 170, member A (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q23.1
Chromosome location (bp)	119629559 - 119635822
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164334 (version 83.38)
Entrez gene	340069
UniProt	A1A519 (UniProt - Evidence at transcript level)
neXtProt	NX_A1A519
Antibodypedia	FAM170A antibodies

PROTEIN BROWSER

FAM170A-001	FAM170A-002	FAM170A-201	FAM170A-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM170A-001 ENSP00000422684 ENST00000515256	A1A519 [Direct mapping] Protein FAM170A Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006366 [transcription from RNA polymerase II promoter] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	330 aa 37.2 kDa	No	0
FAM170A-002 ENSP00000423697 ENST00000509264	A2VCN0 [Direct mapping] FAM170A protein; Protein FAM170A Show all	Predicted intracellular proteins Show all		186 aa 20.9 kDa	No	0
FAM170A-201 ENSP00000482552 ENST00000613773	A1A519 [Direct mapping] Protein FAM170A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006366 [transcription from RNA polymerase II promoter] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	329 aa 37.1 kDa	No	0
FAM170A-202 ENSP00000483075 ENST00000620555	A1A519 [Direct mapping] Protein FAM170A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006366 [transcription from RNA polymerase II promoter] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	282 aa 32.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.