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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

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Reliability

Reliability

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Method

Validation

Method

Validation

Method

Validation

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Searches

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Cancer

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Tissue

Detectable

Cell line

Detectable

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Detectable

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Score

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Antibodies

Column

 
 
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FOXQ1
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PATHOLOGY ATLAS

GENE/PROTEIN

Dictionary

GENERAL INFORMATION

Gene name

FOXQ1

Gene description

Forkhead box Q1

Protein class

Cancer-related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (CACO-2, HaCaT, Hep G2, RT4)
HPA (normal tissue):Tissue enhanced (stomach, urinary bladder)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

Pending cancer tissue analysis.

PROGNOSTIC SUMMARY

Prognostic marker in prostate cancer (favourable).
Prostate cancer p<0.001
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis


STAINING SUMMARY

 

GENE INFORMATION

Gene name

FOXQ1 (HGNC Symbol)

Synonyms

HFH1

Description

Forkhead box Q1 (HGNC Symbol)

Entrez gene summary

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009]

Chromosome

6

Cytoband

p25.3

Chromosome location (bp)

1312473 - 1314187

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164379 (version 83.38)

Entrez gene

94234

UniProt

Q9C009 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9C009

Antibodypedia

FOXQ1 antibodies

PROTEIN BROWSER

FOXQ1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOXQ1-001
ENSP00000296839
ENST00000296839
Q9C009 [Direct mapping]
Forkhead box protein Q1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0030154 [cell differentiation]
GO:0031069 [hair follicle morphogenesis]
GO:0043565 [sequence-specific DNA binding]
Show all
403 aa
41.5 kDa
No 0

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