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FOXQ1

GENERAL INFORMATION

Gene name

 FOXQ1

Gene description

 Forkhead box Q1

Protein class

 Cancer-related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (CACO-2, HaCaT, Hep G2, RT4)
HPA (normal tissue):Tissue enhanced (stomach, urinary bladder)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in prostate cancer (favourable).
Prostate cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 FOXQ1 (HGNC Symbol)

Synonyms

 HFH1

Description

 Forkhead box Q1 (HGNC Symbol)

Entrez gene summary

 FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009]

Chromosome

 6

Cytoband

 p25.3

Chromosome location (bp)

 1312473 - 1314187

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164379 (version 83.38)

Entrez gene

 94234

UniProt

 Q9C009 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9C009

Antibodypedia

 FOXQ1 antibodies

PROTEIN BROWSER
FOXQ1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FOXQ1-001
ENSP00000296839
ENST00000296839
Q9C009 [Direct mapping]
Forkhead box protein Q1
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
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GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0030154 [cell differentiation]
GO:0031069 [hair follicle morphogenesis]
GO:0043565 [sequence-specific DNA binding]
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 403 aa
41.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.