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Most cancers displayed weak to moderate cytoplasmic positivity. The majority of skin cancers along with a few hepatocellular carcinomas, cervical, colorectal and urothelial cancers were strongly stained. Several non-Hodgkins lymphomas were negative.
GENE INFORMATION
Gene name
UQCRQ (HGNC Symbol)
Synonyms
QCR8, QP-C, UQCR7
Description
Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa (HGNC Symbol)
Entrez gene summary
This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]
MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)