Fields »
ABOUT
HELP
BLOG
NEUROD6

GENERAL INFORMATION

Gene name

 NEUROD6

Gene description

 Neuronal differentiation 6

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Cell line enriched (SCLC-21H)
HPA (normal tissue):Tissue enriched (cerebral cortex)

Protein evidence

 Evidence at transcript level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 NEUROD6 (HGNC Symbol)

Synonyms

 Atoh2, bHLHa2, Math-2, Nex1, NEX1M

Description

 Neuronal differentiation 6 (HGNC Symbol)

Entrez gene summary

 This gene is a member of the NEUROD family of basic helix-loop-helix transcription factors. The encoded protein may be involved in the development and differentiation of the nervous system. [provided by RefSeq, Nov 2012]

Chromosome

 7

Cytoband

 p14.3

Chromosome location (bp)

 31337461 - 31340894

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000164600 (version 83.38)

Entrez gene

 63974

UniProt

 Q96NK8 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q96NK8

Antibodypedia

 NEUROD6 antibodies

PROTEIN BROWSER
NEUROD6-001
NEUROD6-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NEUROD6-001
ENSP00000297142
ENST00000297142
Q96NK8 [Direct mapping]
Neurogenic differentiation factor 6
A0A090N7T3 [Target identity:100%; Query identity:100%]
Neurogenic differentiation factor
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0005634 [nucleus]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0021542 [dentate gyrus development]
GO:0030154 [cell differentiation]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046983 [protein dimerization activity]
Show all
 337 aa
38.7 kDa 		No 0
NEUROD6-201
ENSP00000479428
ENST00000611245
A0A087WVG7 [Direct mapping]
Neurogenic differentiation factor
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007399 [nervous system development]
GO:0030154 [cell differentiation]
GO:0046983 [protein dimerization activity]
Show all
 330 aa
37.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.