Tissue expression of SP8 - Summary - The Human Protein Atlas

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SP8

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SP8
Gene description	Sp8 transcription factor
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (prostate)
GTEx:	Tissue enhanced (prostate)
FANTOM5:	Group enriched (hippocampus, prostate)

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA054006
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (prostate)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (prostate)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (hippocampus, prostate)

GENE INFORMATION
Gene name	SP8
Synonyms
Description	Sp8 transcription factor (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an SP family transcription factor that in mouse has been shown to be essential for proper limb development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Chromosome	7
Cytoband	p21.1
Chromosome location (bp)	20782283 - 20786886
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000164651 (version 83.38)
Entrez gene	221833
UniProt	Q8IXZ3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IXZ3
Antibodypedia	SP8 antibodies

PROTEIN BROWSER

SP8-001	SP8-002	SP8-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SP8-001 ENSP00000408792 ENST00000418710	Q8IXZ3 [Direct mapping] Transcription factor Sp8 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0009953 [dorsal/ventral pattern formation] GO:0009954 [proximal/distal pattern formation] GO:0030326 [embryonic limb morphogenesis] GO:0046872 [metal ion binding] Show all	508 aa 50.5 kDa	No	0
SP8-002 ENSP00000354482 ENST00000361443	Q8IXZ3 [Direct mapping] Transcription factor Sp8 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	490 aa 48.7 kDa	No	0
SP8-201 ENSP00000483588 ENST00000617581	A0A087X0Q6 [Direct mapping] Sp8 transcription factor, isoform CRA_d; Transcription factor Sp8 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	466 aa 47.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.