Expression of MIOS in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MIOS

TISSUE

premium

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MIOS
Gene description	Missing oocyte, meiosis regulator, homolog (Drosophila)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA042928
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), endometrial cancer (favourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Endometrial cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042928

GENE INFORMATION
Gene name	MIOS (HGNC Symbol)
Synonyms	FLJ20323
Description	Missing oocyte, meiosis regulator, homolog (Drosophila) (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	p21.3
Chromosome location (bp)	7566872 - 7608929
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164654 (version 83.38)
Entrez gene	54468
UniProt	Q9NXC5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NXC5
Antibodypedia	MIOS antibodies

PROTEIN BROWSER

MIOS-001	MIOS-002	MIOS-005	MIOS-006	MIOS-008	MIOS-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MIOS-001 ENSP00000339881 ENST00000340080	Q9NXC5 [Direct mapping] WD repeat-containing protein mio A0A024RA24 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005765 [lysosomal membrane] GO:0030054 [cell junction] GO:0032008 [positive regulation of TOR signaling] GO:0034198 [cellular response to amino acid starvation] GO:0034629 [cellular protein complex localization] GO:0061700 [GATOR2 complex] Show all	875 aa 98.6 kDa	No	0
MIOS-002 ENSP00000384088 ENST00000405785	Q9NXC5 [Direct mapping] WD repeat-containing protein mio A0A024RA24 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005765 [lysosomal membrane] GO:0030054 [cell junction] GO:0032008 [positive regulation of TOR signaling] GO:0034198 [cellular response to amino acid starvation] GO:0034629 [cellular protein complex localization] GO:0061700 [GATOR2 complex] Show all	875 aa 98.6 kDa	No	0
MIOS-005 ENSP00000410752 ENST00000456533	C9JAQ1 [Direct mapping] WD repeat-containing protein mio Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	179 aa 20 kDa	No	0
MIOS-006 ENSP00000413050 ENST00000433635	C9JTV2 [Direct mapping] WD repeat-containing protein mio Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	150 aa 16.7 kDa	No	0
MIOS-008 ENSP00000407518 ENST00000433056	C9JUE6 [Direct mapping] WD repeat-containing protein mio Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		64 aa 7.1 kDa	No	0
MIOS-009 ENSP00000413489 ENST00000445169	C9JUE6 [Direct mapping] WD repeat-containing protein mio Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		64 aa 7.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.