Fields »
ABOUT
HELP
BLOG
FABP5

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 FABP5

Gene description

 Fatty acid binding protein 5 (psoriasis-associated)

Protein class

 Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the cytosol. In addition localized to the plasma membrane.

RNA cell category

 Mixed

Protein evidence

 Evidence at protein level

Main location

 Localized to the Cytosol (supported)

Additional location

 In addition localized to the Plasma membrane (approved)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
CAB040577
SHOW MORE

ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the cytosol. In addition localized to the plasma membrane.

Main location

 Cytosol (supported)

Additional location

 Plasma membrane (approved)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
CAB040577 A-431 Plasma membrane
Cytosol
CAB040577 U-2 OS Plasma membrane
Cytosol

GENE INFORMATION

Gene name

 FABP5 (HGNC Symbol)

Synonyms

 E-FABP, KFABP, PA-FABP

Description

 Fatty acid binding protein 5 (psoriasis-associated) (HGNC Symbol)

Entrez gene summary

 This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]

Chromosome

 8

Cytoband

 q21.13

Chromosome location (bp)

 81280363 - 81284777

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164687 (version 83.38)

Entrez gene

 2171

UniProt

 Q01469 (UniProt - Evidence at protein level)

neXtProt

 NX_Q01469

Antibodypedia

 FABP5 antibodies

PROTEIN BROWSER
FABP5-001
FABP5-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FABP5-001
ENSP00000297258
ENST00000297258
Q01469 [Direct mapping]
Fatty acid-binding protein, epidermal
E7DVW5 [Target identity:100%; Query identity:100%]
Fatty acid binding protein 5 (Psoriasis-associated)
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005215 [transporter activity]
GO:0005504 [fatty acid binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006006 [glucose metabolic process]
GO:0006629 [lipid metabolic process]
GO:0006656 [phosphatidylcholine biosynthetic process]
GO:0006810 [transport]
GO:0008289 [lipid binding]
GO:0008544 [epidermis development]
GO:0015758 [glucose transport]
GO:0019433 [triglyceride catabolic process]
GO:0044281 [small molecule metabolic process]
GO:0070062 [extracellular exosome]
Show all
 135 aa
15.2 kDa 		No 0
FABP5-002
ENSP00000379647
ENST00000396359
I6L8B7 [Direct mapping]
Fatty acid-binding protein, epidermal
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005215 [transporter activity]
GO:0006810 [transport]
GO:0008289 [lipid binding]
Show all
 101 aa
11.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.