We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
SRY (sex determining region Y)-box 17 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008]
Predicted intracellular proteins Transcription factors Other all-alpha-helical DNA-binding domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0001525 [angiogenesis] GO:0001570 [vasculogenesis] GO:0001706 [endoderm formation] GO:0001828 [inner cell mass cellular morphogenesis] GO:0001947 [heart looping] GO:0003142 [cardiogenic plate morphogenesis] GO:0003143 [embryonic heart tube morphogenesis] GO:0003151 [outflow tract morphogenesis] GO:0003308 [negative regulation of Wnt signaling pathway involved in heart development] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0007369 [gastrulation] GO:0007492 [endoderm development] GO:0007493 [endodermal cell fate determination] GO:0008013 [beta-catenin binding] GO:0008134 [transcription factor binding] GO:0010628 [positive regulation of gene expression] GO:0021903 [rostrocaudal neural tube patterning] GO:0023019 [signal transduction involved in regulation of gene expression] GO:0030178 [negative regulation of Wnt signaling pathway] GO:0030308 [negative regulation of cell growth] GO:0031648 [protein destabilization] GO:0035050 [embryonic heart tube development] GO:0042074 [cell migration involved in gastrulation] GO:0042661 [regulation of mesodermal cell fate specification] GO:0042662 [negative regulation of mesodermal cell fate specification] GO:0042789 [mRNA transcription from RNA polymerase II promoter] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044798 [nuclear transcription factor complex] GO:0045595 [regulation of cell differentiation] GO:0045597 [positive regulation of cell differentiation] GO:0045732 [positive regulation of protein catabolic process] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0045995 [regulation of embryonic development] GO:0046982 [protein heterodimerization activity] GO:0048568 [embryonic organ development] GO:0048617 [embryonic foregut morphogenesis] GO:0048643 [positive regulation of skeletal muscle tissue development] GO:0048863 [stem cell differentiation] GO:0048866 [stem cell fate specification] GO:0050821 [protein stabilization] GO:0060070 [canonical Wnt signaling pathway] GO:0060214 [endocardium formation] GO:0060807 [regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification] GO:0060913 [cardiac cell fate determination] GO:0060914 [heart formation] GO:0060956 [endocardial cell differentiation] GO:0061009 [common bile duct development] GO:0061010 [gall bladder development] GO:0061031 [endodermal digestive tract morphogenesis] GO:0072001 [renal system development] GO:0072091 [regulation of stem cell proliferation] GO:0090090 [negative regulation of canonical Wnt signaling pathway] GO:2000035 [regulation of stem cell division] GO:2000043 [regulation of cardiac cell fate specification]