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KCNV1

GENERAL INFORMATION

Gene name

 KCNV1

Gene description

 Potassium channel, voltage gated modifier subfamily V, member 1

Protein class

 Predicted membrane proteins
Voltage-gated ion channels

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enhanced (renal cancer)
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (cerebral cortex)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enhanced (renal cancer)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 KCNV1 (HGNC Symbol)

Synonyms

 Kv8.1

Description

 Potassium channel, voltage gated modifier subfamily V, member 1 (HGNC Symbol)

Entrez gene summary

 Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This protein is essentially present in the brain, and its role might be to inhibit the function of a particular class of outward rectifier potassium channel types. [provided by RefSeq, Jul 2008]

Chromosome

 8

Cytoband

 q23.2

Chromosome location (bp)

 109963645 - 109975847

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164794 (version 83.38)

Entrez gene

 27012

UniProt

 Q6PIU1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6PIU1

Antibodypedia

 KCNV1 antibodies

PROTEIN BROWSER
KCNV1-001
KCNV1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KCNV1-001
ENSP00000435954
ENST00000524391
Q6PIU1 [Direct mapping]
Potassium voltage-gated channel subfamily V member 1
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Voltage-gated ion channels
   Voltage-Gated Potassium Channels
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
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GO:0005216 [ion channel activity]
GO:0005251 [delayed rectifier potassium channel activity]
GO:0005267 [potassium channel activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006813 [potassium ion transport]
GO:0007268 [synaptic transmission]
GO:0008076 [voltage-gated potassium channel complex]
GO:0008200 [ion channel inhibitor activity]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0034765 [regulation of ion transmembrane transport]
GO:0051260 [protein homooligomerization]
GO:0055085 [transmembrane transport]
GO:0071805 [potassium ion transmembrane transport]
Show all
 500 aa
56.3 kDa 		No 5
KCNV1-201
ENSP00000297404
ENST00000297404
Q6PIU1 [Direct mapping]
Potassium voltage-gated channel subfamily V member 1
Show all
Voltage-gated ion channels
   Voltage-Gated Potassium Channels
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Show all
GO:0005216 [ion channel activity]
GO:0005251 [delayed rectifier potassium channel activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006813 [potassium ion transport]
GO:0007268 [synaptic transmission]
GO:0008076 [voltage-gated potassium channel complex]
GO:0008200 [ion channel inhibitor activity]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0034765 [regulation of ion transmembrane transport]
GO:0051260 [protein homooligomerization]
GO:0055085 [transmembrane transport]
GO:0071805 [potassium ion transmembrane transport]
Show all
 500 aa
56.3 kDa 		No 5

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.