Expression of CSMD3 in cancer - Summary - The Human Protein Atlas

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CSMD3

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CSMD3
Gene description	CUB and Sushi multiple domains 3
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (cerebral cortex, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA029007
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA029007

GENE INFORMATION
Gene name	CSMD3
Synonyms
Description	CUB and Sushi multiple domains 3 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q23.3
Chromosome location (bp)	112222928 - 113437099
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000164796 (version 83.38)
Entrez gene	114788
UniProt	Q7Z407 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z407
Antibodypedia	CSMD3 antibodies

PROTEIN BROWSER

CSMD3-001	CSMD3-002	CSMD3-006	CSMD3-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CSMD3-001 ENSP00000297405 ENST00000297405	Q7Z407 [Direct mapping] CUB and sushi domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] Show all	3707 aa 406 kDa	No	1
CSMD3-002 ENSP00000412263 ENST00000455883	Q7Z407 [Direct mapping] CUB and sushi domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] Show all	3538 aa 387.3 kDa	No	1
CSMD3-006 ENSP00000345799 ENST00000343508	Q7Z407 [Direct mapping] CUB and sushi domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] Show all	3667 aa 401.6 kDa	No	1
CSMD3-007 ENSP00000341558 ENST00000339701	H7BXX0 [Direct mapping] CUB and sushi domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	2977 aa 325.6 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.