Tissue expression of SPAG11B - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	SPAG11B
Gene description	Sperm associated antigen 11B
Protein class	Predicted intracellular proteins Predicted secreted proteins Transporters
Predicted localization	Intracellular,Secreted
Number of transcripts	8
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (epididymis)
GTEx:	Not detected

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (epididymis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	SPAG11B (HGNC Symbol)
Synonyms	EDDM2B, EP2, EP2C, EP2D, HE2
Description	Sperm associated antigen 11B (HGNC Symbol)
Entrez gene summary	This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	p23.1
Chromosome location (bp)	7442684 - 7463674
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000164871 (version 83.38)
Entrez gene	10407
UniProt	Q08648 (UniProt - Evidence at transcript level)
neXtProt	NX_Q08648
Antibodypedia	SPAG11B antibodies

PROTEIN BROWSER

SPAG11B-001	SPAG11B-002	SPAG11B-003	SPAG11B-004	SPAG11B-005	SPAG11B-006	SPAG11B-007	SPAG11B-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPAG11B-001 ENSP00000352797 ENST00000359758	A0A0A0MRG4 [Direct mapping] Sperm-associated antigen 11B Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] Show all	108 aa 12 kDa	Yes	0
SPAG11B-002 ENSP00000354411 ENST00000361111		Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] Show all	82 aa 9.1 kDa	Yes	0
SPAG11B-003 ENSP00000297498 ENST00000297498	Q08648 [Direct mapping] Sperm-associated antigen 11B Show all	Transporters Transporter channels and pores Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0003674 [molecular_function] GO:0005576 [extracellular region] GO:0007283 [spermatogenesis] Show all	103 aa 11.4 kDa	Yes	0
SPAG11B-004 ENSP00000322591 ENST00000317900	Q08648 [Direct mapping] Sperm-associated antigen 11B Show all	Transporters Transporter channels and pores Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0003674 [molecular_function] GO:0005576 [extracellular region] GO:0006952 [defense response] GO:0007283 [spermatogenesis] Show all	113 aa 12.7 kDa	Yes	0
SPAG11B-005 ENSP00000431230 ENST00000528168	Q08648 [Direct mapping] Sperm-associated antigen 11B Show all	Transporters Transporter channels and pores Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0003674 [molecular_function] GO:0005576 [extracellular region] GO:0007283 [spermatogenesis] Show all	50 aa 5.7 kDa	Yes	0
SPAG11B-006 ENSP00000398550 ENST00000458665	Q08648 [Direct mapping] Sperm-associated antigen 11B Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0003674 [molecular_function] GO:0005576 [extracellular region] GO:0006952 [defense response] GO:0007283 [spermatogenesis] Show all	80 aa 9.1 kDa	Yes	0
SPAG11B-007 ENSP00000381480 ENST00000398462	A8MZA0 [Direct mapping] Sperm-associated antigen 11B Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0006952 [defense response] GO:0042742 [defense response to bacterium] Show all	133 aa 14.8 kDa	Yes	0
SPAG11B-009 ENSP00000437154 ENST00000528943	H0YF39 [Direct mapping] Sperm-associated antigen 11B Show all	Predicted intracellular proteins Show all	GO:0005576 [extracellular region] Show all	106 aa 11.8 kDa	No	0