Expression of C7orf55 in cancer - Summary - The Human Protein Atlas

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C7orf55

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C7orf55
Gene description	Chromosome 7 open reading frame 55
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several cell types.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Approved based on 2 antibodies. HPA045663 , HPA050553
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PROGNOSTIC SUMMARY
Prognostic marker in ovarian cancer (favourable), renal cancer (favourable) and lung cancer (favourable).
Ovarian cancer p<0.001 Renal cancer p<0.001 Lung cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA045663	HPA050553

GENE INFORMATION
Gene name	C7orf55 (HGNC Symbol)
Synonyms	FMC1, HSPC268
Description	Chromosome 7 open reading frame 55 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q34
Chromosome location (bp)	139339457 - 139346319
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164898 (version 83.38)
Entrez gene	154791
UniProt	Q96HJ9 (UniProt - Evidence at protein level)
neXtProt	NX_Q96HJ9
Antibodypedia	C7orf55 antibodies

PROTEIN BROWSER

C7orf55-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C7orf55-001 ENSP00000297534 ENST00000297534	Q96HJ9 [Direct mapping] UPF0562 protein C7orf55 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] Show all	113 aa 12.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.