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DCSTAMP

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GENERAL INFORMATION

Gene name

 DCSTAMP

Gene description

 Dendrocyte expressed seven transmembrane protein

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Not detected

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 DCSTAMP (HGNC Symbol)

Synonyms

 DC-STAMP, FIND, TM7SF4

Description

 Dendrocyte expressed seven transmembrane protein (HGNC Symbol)

Entrez gene summary

 This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

Chromosome

 8

Cytoband

 q22.3

Chromosome location (bp)

 104339087 - 104356689

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164935 (version 83.38)

Entrez gene

 81501

UniProt

 Q9H295 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H295

Antibodypedia

 DCSTAMP antibodies

PROTEIN BROWSER
DCSTAMP-001
DCSTAMP-007
DCSTAMP-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DCSTAMP-001
ENSP00000297581
ENST00000297581
Q9H295 [Direct mapping]
Dendritic cell-specific transmembrane protein
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Show all
GO:0005515 [protein binding]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005887 [integral component of plasma membrane]
GO:0009986 [cell surface]
GO:0010008 [endosome membrane]
GO:0016021 [integral component of membrane]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0030308 [negative regulation of cell growth]
GO:0030316 [osteoclast differentiation]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0034241 [positive regulation of macrophage fusion]
GO:0036006 [cellular response to macrophage colony-stimulating factor stimulus]
GO:0043011 [myeloid dendritic cell differentiation]
GO:0045657 [positive regulation of monocyte differentiation]
GO:0045780 [positive regulation of bone resorption]
GO:0061025 [membrane fusion]
GO:0071353 [cellular response to interleukin-4]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0072675 [osteoclast fusion]
Show all
 470 aa
53.4 kDa 		No 5
DCSTAMP-007
ENSP00000428869
ENST00000517991
Q9H295 [Direct mapping]
Dendritic cell-specific transmembrane protein
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Show all
GO:0005515 [protein binding]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005887 [integral component of plasma membrane]
GO:0009986 [cell surface]
GO:0010008 [endosome membrane]
GO:0016021 [integral component of membrane]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0030308 [negative regulation of cell growth]
GO:0030316 [osteoclast differentiation]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0034241 [positive regulation of macrophage fusion]
GO:0036006 [cellular response to macrophage colony-stimulating factor stimulus]
GO:0043011 [myeloid dendritic cell differentiation]
GO:0045657 [positive regulation of monocyte differentiation]
GO:0045780 [positive regulation of bone resorption]
GO:0061025 [membrane fusion]
GO:0071353 [cellular response to interleukin-4]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0072675 [osteoclast fusion]
Show all
 283 aa
31.6 kDa 		No 3
DCSTAMP-201
ENSP00000480546
ENST00000622554
Q9H295 [Direct mapping]
Dendritic cell-specific transmembrane protein
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Show all
GO:0005515 [protein binding]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005887 [integral component of plasma membrane]
GO:0009986 [cell surface]
GO:0010008 [endosome membrane]
GO:0016021 [integral component of membrane]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0030308 [negative regulation of cell growth]
GO:0030316 [osteoclast differentiation]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0034241 [positive regulation of macrophage fusion]
GO:0036006 [cellular response to macrophage colony-stimulating factor stimulus]
GO:0043011 [myeloid dendritic cell differentiation]
GO:0045657 [positive regulation of monocyte differentiation]
GO:0045780 [positive regulation of bone resorption]
GO:0061025 [membrane fusion]
GO:0071353 [cellular response to interleukin-4]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0072675 [osteoclast fusion]
Show all
 283 aa
31.6 kDa 		No 3

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.