Expression of KIAA1161 in cancer - Summary - The Human Protein Atlas

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KIAA1161

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KIAA1161
Gene description	KIAA1161
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (SK-BR-3, T-47d)
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA060533
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and endometrial cancer (unfavourable).
Renal cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA060533

GENE INFORMATION
Gene name	KIAA1161 (HGNC Symbol)
Synonyms	NET37
Description	KIAA1161 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p13.3
Chromosome location (bp)	34366670 - 34376853
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164976 (version 83.38)
Entrez gene	57462
UniProt	Q6NSJ0 (UniProt - Evidence at protein level)
neXtProt	NX_Q6NSJ0
Antibodypedia	KIAA1161 antibodies

PROTEIN BROWSER

KIAA1161-001	KIAA1161-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KIAA1161-001 ENSP00000297625 ENST00000297625	Q6NSJ0 [Direct mapping] Uncharacterized family 31 glucosidase KIAA1161 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds] GO:0005515 [protein binding] GO:0005975 [carbohydrate metabolic process] GO:0016021 [integral component of membrane] GO:0031965 [nuclear membrane] GO:0043568 [positive regulation of insulin-like growth factor receptor signaling pathway] GO:0048741 [skeletal muscle fiber development] GO:0051897 [positive regulation of protein kinase B signaling] Show all	714 aa 81.1 kDa	No	1
KIAA1161-002 ENSP00000368437 ENST00000379142	X6RA92 [Direct mapping] Uncharacterized family 31 glucosidase KIAA1161 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	160 aa 17.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.