Expression of C8orf34 in cancer - Summary - The Human Protein Atlas

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C8orf34

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C8orf34
Gene description	Chromosome 8 open reading frame 34
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HEK93, RH-30)
HPA (normal tissue):	Tissue enhanced (fallopian tube, parathyroid gland)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA044420
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044420

GENE INFORMATION
Gene name	C8orf34 (HGNC Symbol)
Synonyms	vest-1, VEST1
Description	Chromosome 8 open reading frame 34 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q13.2
Chromosome location (bp)	68330722 - 68819022
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165084 (version 83.38)
Entrez gene	116328
UniProt	Q49A92 (UniProt - Evidence at transcript level)
neXtProt	NX_Q49A92
Antibodypedia	C8orf34 antibodies

PROTEIN BROWSER

C8orf34-001	C8orf34-002	C8orf34-003	C8orf34-004	C8orf34-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C8orf34-001 ENSP00000427820 ENST00000518698	Q49A92 [Direct mapping] Uncharacterized protein C8orf34 Show all	Predicted intracellular proteins Show all		538 aa 59.4 kDa	No	0
C8orf34-002 ENSP00000337174 ENST00000337103	Q49A92 [Direct mapping] Uncharacterized protein C8orf34 Show all	Predicted intracellular proteins Show all		427 aa 47.6 kDa	No	0
C8orf34-003 ENSP00000345255 ENST00000348340	A0A0C4DFS7 [Direct mapping] Uncharacterized protein C8orf34 Show all	Predicted intracellular proteins Show all		287 aa 32.5 kDa	No	0
C8orf34-004 ENSP00000319532 ENST00000325233	Q49A92 [Direct mapping] Uncharacterized protein C8orf34 Show all	Predicted intracellular proteins Show all		201 aa 22.3 kDa	No	0
C8orf34-005 ENSP00000429102 ENST00000523686	Q49A92 [Direct mapping] Uncharacterized protein C8orf34 Show all	Predicted intracellular proteins Show all		129 aa 14.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.