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RASEF

GENERAL INFORMATION

Gene name

 RASEF

Gene description

 RAS and EF-hand domain containing

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Mixed
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 RASEF (HGNC Symbol)

Synonyms

 FLJ31614, RAB45

Description

 RAS and EF-hand domain containing (HGNC Symbol)

Entrez gene summary

 This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012]

Chromosome

 9

Cytoband

 q21.32

Chromosome location (bp)

 82979585 - 83063177

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000165105 (version 83.38)

Entrez gene

 158158

UniProt

 Q8IZ41 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8IZ41

Antibodypedia

 RASEF antibodies

PROTEIN BROWSER
RASEF-001
RASEF-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RASEF-001
ENSP00000365630
ENST00000376447
Q8IZ41 [Direct mapping]
Ras and EF-hand domain-containing protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003924 [GTPase activity]
GO:0005509 [calcium ion binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
GO:0048471 [perinuclear region of cytoplasm]
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 740 aa
82.9 kDa 		No 0
RASEF-002
ENSP00000345651
ENST00000340717
Q8IZ41 [Direct mapping]
Ras and EF-hand domain-containing protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005509 [calcium ion binding]
GO:0005525 [GTP binding]
GO:0006886 [intracellular protein transport]
GO:0032482 [Rab protein signal transduction]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 189 aa
20.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.