Fields »
ABOUT
HELP
BLOG
PDZD8

GENERAL INFORMATION

Gene name

 PDZD8

Gene description

 PDZ domain containing 8

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA015716
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (unfavourable).
Pancreatic cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA015716

GENE INFORMATION

Gene name

 PDZD8 (HGNC Symbol)

Synonyms

 bA129M16.2, FLJ34427, PDZK8

Description

 PDZ domain containing 8 (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

Chromosome location (bp)

 117277274 - 117375467

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000165650 (version 83.38)

Entrez gene

 118987

UniProt

 Q8NEN9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NEN9

Antibodypedia

 PDZD8 antibodies

PROTEIN BROWSER
PDZD8-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PDZD8-001
ENSP00000334642
ENST00000334464
Q8NEN9 [Direct mapping]
PDZ domain-containing protein 8
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0007010 [cytoskeleton organization]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0022604 [regulation of cell morphogenesis]
GO:0035556 [intracellular signal transduction]
GO:0046872 [metal ion binding]
Show all
 1154 aa
128.6 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.