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Most cancer tissues displayed moderate immunoreactivity. Strong staining was observed in most colorectal, testicular, urothelial and several breast cancers. Several gliomas and lymphomas were weakly stained or negative.
Most cancers showed weak to moderate cytoplasmic and membranous positivity. Rare cases of ovarian and cervical showed strong positivity. A majority of gliomas was weakly stained or negative.
ZMYND19 is a MYND zinc finger domain-containing protein that binds to the C terminus of melanin-concentrating hormone receptor-1 (MCHR1; MIM 601751) (Bachner et al., 2002 [PubMed 12208518]), and to the N termini of alpha-tubulin (TUBA1; MIM 191110), and beta-tubulin (TUBB; MIM 191130) (Francke et al., 2005 [PubMed 16039987]).[supplied by OMIM, Mar 2008]