A majority of malignant cells were weakly stained or negative. Most endometrial cancers along with several cases of ovarian cancers and malignant melanomas showed moderate cytoplasmic immunoreactivity.
Moderate immunoreactivity was observed in most liver and renal cancers as well as several urothelial and gastric cancers cancers. Malignant cells in general showed weak staining or were negative.
KCNC2 (HGNC Symbol)
Potassium channel, voltage gated Shaw related subfamily C, member 2 (HGNC Symbol)
Entrez gene summary
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]