Expression of DEPDC4 in cancer - Summary - The Human Protein Atlas

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DEPDC4

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	DEPDC4
Gene description	DEP domain containing 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA039323
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039323

GENE INFORMATION
Gene name	DEPDC4 (HGNC Symbol)
Synonyms	DEP.4, FLJ33505
Description	DEP domain containing 4 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q23.1
Chromosome location (bp)	100203669 - 100267079
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166153 (version 83.38)
Entrez gene	120863
UniProt	Q8N2C3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N2C3
Antibodypedia	DEPDC4 antibodies

PROTEIN BROWSER

DEPDC4-001	DEPDC4-002	DEPDC4-005	DEPDC4-007	DEPDC4-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DEPDC4-001 ENSP00000396234 ENST00000416321	Q8N2C3 [Direct mapping] DEP domain-containing protein 4 A0A024RBI9 [Target identity:100%; Query identity:100%] DEP domain containing 4, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] Show all	294 aa 33.7 kDa	No	0
DEPDC4-002 ENSP00000448385 ENST00000550587	E9PGM3 [Direct mapping] DEP domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] Show all	387 aa 44.7 kDa	No	0
DEPDC4-005 ENSP00000448338 ENST00000549249	Q3ZCN8 [Direct mapping] DEP domain-containing protein 4; DEPDC4 protein Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] Show all	333 aa 38.6 kDa	No	0
DEPDC4-007 ENSP00000449590 ENST00000551642	H0YIL0 [Direct mapping] DEP domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] Show all	286 aa 32.8 kDa	No	0
DEPDC4-008 ENSP00000448728 ENST00000548313	H0YI71 [Direct mapping] DEP domain-containing protein 4 Show all	Predicted intracellular proteins Show all		105 aa 11.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.