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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

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Score

Score

Score

Antibodies

Column

 
 
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OPN1MW2
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

OPN1MW2

Gene description

Opsin 1 (cone pigments), medium-wave-sensitive 2

Protein class

Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Not detected
GTEx:Not detected

Protein evidence

Evidence at protein level

DATA RELIABILITY

Reliability score

Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW

Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected

GENE INFORMATION

Gene name

OPN1MW2

Synonyms

Description

Opsin 1 (cone pigments), medium-wave-sensitive 2 (HGNC Symbol)

Entrez gene summary

This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]

Chromosome

X

Cytoband

q28

Chromosome location (bp)

154219756 - 154233286

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166160 (version 83.38)

Entrez gene

728458

UniProt

P04001 (UniProt - Evidence at protein level)

neXtProt

NX_P04001

Antibodypedia

OPN1MW2 antibodies

PROTEIN BROWSER

OPN1MW2-001
OPN1MW2-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OPN1MW2-001
ENSP00000358945
ENST00000369929
P04001 [Direct mapping]
Medium-wave-sensitive opsin 1
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
   Opsins
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Disease related genes
Potential drug targets
Show all
GO:0001523 [retinoid metabolic process]
GO:0004930 [G-protein coupled receptor activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007601 [visual perception]
GO:0007603 [phototransduction, visible light]
GO:0009881 [photoreceptor activity]
GO:0016021 [integral component of membrane]
GO:0018298 [protein-chromophore linkage]
GO:0032467 [positive regulation of cytokinesis]
GO:0042622 [photoreceptor outer segment membrane]
Show all
364 aa
40.6 kDa
No 7
OPN1MW2-002
ENSP00000403023
ENST00000430419
H0Y642 [Direct mapping]
Medium-wave-sensitive opsin 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Show all
GO:0004930 [G-protein coupled receptor activity]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007601 [visual perception]
GO:0007602 [phototransduction]
GO:0016021 [integral component of membrane]
Show all
164 aa
18.1 kDa
No 2

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