Expression of AKIP1 in cancer - Summary - The Human Protein Atlas

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AKIP1

TISSUE

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CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	AKIP1
Gene description	A kinase (PRKA) interacting protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and endometrial cancer (favourable).
Liver cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	AKIP1 (HGNC Symbol)
Synonyms	BCA3, C11orf17
Description	A kinase (PRKA) interacting protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
Chromosome	11
Cytoband	p15.4
Chromosome location (bp)	8911139 - 8920084
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166452 (version 83.38)
Entrez gene	56672
UniProt	Q9NQ31 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQ31
Antibodypedia	AKIP1 antibodies

PROTEIN BROWSER

AKIP1-001	AKIP1-002	AKIP1-003	AKIP1-004	AKIP1-005	AKIP1-006	AKIP1-007	AKIP1-008	AKIP1-009	AKIP1-010	AKIP1-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AKIP1-001 ENSP00000310459 ENST00000309377	Q9NQ31 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0034446 [substrate adhesion-dependent cell spreading] Show all	210 aa 23.1 kDa	No	0
AKIP1-002 ENSP00000433510 ENST00000525005	B4DGE2 [Direct mapping] A-kinase-interacting protein 1; cDNA FLJ55419, highly similar to Proline-rich protein BCA3 Show all	Predicted intracellular proteins Show all	GO:0005654 [nucleoplasm] Show all	195 aa 21.7 kDa	No	0
AKIP1-003 ENSP00000434726 ENST00000529876	E9PN38 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Show all	GO:0005654 [nucleoplasm] Show all	168 aa 18.6 kDa	No	0
AKIP1-004 ENSP00000310644 ENST00000309357	Q9NQ31 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] Show all	183 aa 20.2 kDa	No	0
AKIP1-005 ENSP00000299576 ENST00000299576	Q9NQ31 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] Show all	183 aa 20 kDa	No	0
AKIP1-006 ENSP00000434785 ENST00000524577	E9PNI1 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Show all	GO:0005654 [nucleoplasm] Show all	179 aa 19.9 kDa	No	0
AKIP1-007 ENSP00000434820 ENST00000534506	E9PN38 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Show all	GO:0005654 [nucleoplasm] Show all	168 aa 18.6 kDa	No	0
AKIP1-008 ENSP00000436989 ENST00000530281	E9PPN7 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Show all		101 aa 11.2 kDa	No	0
AKIP1-009 ENSP00000379885 ENST00000396648	Q9NQ31 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] Show all	183 aa 20 kDa	No	0
AKIP1-010 ENSP00000431331 ENST00000534147	Q9NQ31 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] Show all	210 aa 23.1 kDa	No	0
AKIP1-011 ENSP00000431602 ENST00000529942	H0YCH8 [Direct mapping] A-kinase-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005654 [nucleoplasm] Show all	151 aa 16.5 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.