Expression of ATMIN in cancer - Summary - The Human Protein Atlas

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ATMIN

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ATMIN
Gene description	ATM interactor
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Mainly General nuclear and nucleoli expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA066900
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA066900

GENE INFORMATION
Gene name	ATMIN (HGNC Symbol)
Synonyms	ASCIZ, KIAA0431, ZNF822
Description	ATM interactor (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q23.2
Chromosome location (bp)	81035847 - 81047358
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166454 (version 83.38)
Entrez gene	23300
UniProt	O43313 (UniProt - Evidence at protein level)
neXtProt	NX_O43313
Antibodypedia	ATMIN antibodies

PROTEIN BROWSER

ATMIN-001	ATMIN-003	ATMIN-004	ATMIN-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATMIN-001 ENSP00000299575 ENST00000299575	O43313 [Direct mapping] ATM interactor Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006974 [cellular response to DNA damage stimulus] GO:0044212 [transcription regulatory region DNA binding] GO:0045502 [dynein binding] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0060271 [cilium morphogenesis] Show all	823 aa 88.3 kDa	Yes	0
ATMIN-003 ENSP00000463478 ENST00000564241	O43313 [Direct mapping] ATM interactor Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006974 [cellular response to DNA damage stimulus] GO:0045502 [dynein binding] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	667 aa 72.3 kDa	No	0
ATMIN-004 ENSP00000455497 ENST00000566488	O43313 [Direct mapping] ATM interactor Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006974 [cellular response to DNA damage stimulus] GO:0045502 [dynein binding] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	667 aa 72.3 kDa	No	0
ATMIN-005 ENSP00000464427 ENST00000565237	J3QRX7 [Direct mapping] ATM interactor Show all	Predicted intracellular proteins Show all		55 aa 6.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.