Expression of GLYATL1 in cancer - Summary - The Human Protein Atlas

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GLYATL1

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GLYATL1
Gene description	Glycine-N-acyltransferase-like 1
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (liver cancer, prostate cancer, renal cancer)
HPA (cell line):	Cell line enhanced (CACO-2, Daudi, RPTEC TERT1)
HPA (normal tissue):	Group enriched (kidney, liver)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Granular cytoplasmic expression in proximal renal tubules and hepatocytes.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Caution, targets protein from more than one gene. Caution, Splice and/or transcript discrepancy exists.
Reliability score	Supported based on 1 antibody. HPA039501
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and liver cancer (favourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (liver cancer, prostate cancer, renal cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039501

GENE INFORMATION
Gene name	GLYATL1 (HGNC Symbol)
Synonyms	FLJ34646, MGC15397
Description	Glycine-N-acyltransferase-like 1 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q12.1
Chromosome location (bp)	58905398 - 59043527
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166840 (version 83.38)
Entrez gene	92292
UniProt	Q969I3 (UniProt - Evidence at protein level)
neXtProt	NX_Q969I3
Antibodypedia	GLYATL1 antibodies

PROTEIN BROWSER

GLYATL1-001	GLYATL1-002	GLYATL1-013	GLYATL1-016	GLYATL1-018	GLYATL1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GLYATL1-001 ENSP00000300079 ENST00000300079	Q969I3 [Direct mapping] Glycine N-acyltransferase-like protein 1 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0008152 [metabolic process] GO:0047946 [glutamine N-acyltransferase activity] GO:0047961 [glycine N-acyltransferase activity] Show all	333 aa 38.6 kDa	No	0
GLYATL1-002 ENSP00000322223 ENST00000317391	Q969I3 [Direct mapping] Glycine N-acyltransferase-like protein 1 A9ZM15 [Target identity:100%; Query identity:100%] Glycine acyltransferase family-C; Glycine-N-acyltransferase-like 1, isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0008152 [metabolic process] GO:0047946 [glutamine N-acyltransferase activity] GO:0047961 [glycine N-acyltransferase activity] Show all	302 aa 35.1 kDa	No	0
GLYATL1-013 ENSP00000436116 ENST00000532726	E9PR27 [Direct mapping] Glycine N-acyltransferase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0008152 [metabolic process] GO:0047961 [glycine N-acyltransferase activity] Show all	79 aa 9.3 kDa	No	0
GLYATL1-016 ENSP00000434652 ENST00000526351	E9PP99 [Direct mapping] Glycine N-acyltransferase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0008152 [metabolic process] GO:0047961 [glycine N-acyltransferase activity] Show all	173 aa 19.8 kDa	No	0
GLYATL1-018 ENSP00000433716 ENST00000525608	E9PJV1 [Direct mapping] Glycine N-acyltransferase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0008152 [metabolic process] GO:0047961 [glycine N-acyltransferase activity] Show all	68 aa 7.9 kDa	No	0
GLYATL1-201 ENSP00000479741 ENST00000612196	Q969I3 [Direct mapping] Glycine N-acyltransferase-like protein 1 A9ZM15 [Target identity:100%; Query identity:100%] Glycine acyltransferase family-C; Glycine-N-acyltransferase-like 1, isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0008152 [metabolic process] GO:0047946 [glutamine N-acyltransferase activity] GO:0047961 [glycine N-acyltransferase activity] Show all	302 aa 35.1 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.