Expression of BPIFB6 in cancer - Summary - The Human Protein Atlas

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BPIFB6

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	BPIFB6
Gene description	BPI fold containing family B, member 6
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex. External RNA data suggests low expression in minor salivary gland.
Reliability score	Uncertain based on 1 antibody. HPA043057
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043057

GENE INFORMATION
Gene name	BPIFB6 (HGNC Symbol)
Synonyms	BPIL3, LPLUNC6
Description	BPI fold containing family B, member 6 (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	q11.21
Chromosome location (bp)	33031648 - 33044047
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167104 (version 83.38)
Entrez gene	128859
UniProt	Q8NFQ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NFQ5
Antibodypedia	BPIFB6 antibodies

PROTEIN BROWSER

BPIFB6-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BPIFB6-001 ENSP00000344929 ENST00000349552	Q8NFQ5 [Direct mapping] BPI fold-containing family B member 6 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0008289 [lipid binding] Show all	453 aa 49.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.