Tissue expression of ACSF2 - Summary - The Human Protein Atlas

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ACSF2

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ACSF2
Gene description	Acyl-CoA synthetase family member 2
Protein class	Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (kidney)
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA024693
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (kidney)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ACSF2 (HGNC Symbol)
Synonyms	ACSMW, FLJ20920
Description	Acyl-CoA synthetase family member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q21.33
Chromosome location (bp)	50426158 - 50474845
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167107 (version 83.38)
Entrez gene	80221
UniProt	Q96CM8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96CM8
Antibodypedia	ACSF2 antibodies

PROTEIN BROWSER

ACSF2-001	ACSF2-002	ACSF2-004	ACSF2-005	ACSF2-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACSF2-001 ENSP00000300441 ENST00000300441	Q96CM8 [Direct mapping] Acyl-CoA synthetase family member 2, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005759 [mitochondrial matrix] GO:0006631 [fatty acid metabolic process] GO:0008152 [metabolic process] GO:0016874 [ligase activity] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	615 aa 68.1 kDa	No	2
ACSF2-002 ENSP00000401831 ENST00000427954	Q96CM8 [Direct mapping] Acyl-CoA synthetase family member 2, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0006631 [fatty acid metabolic process] GO:0008152 [metabolic process] GO:0016874 [ligase activity] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	640 aa 70.6 kDa	No	2
ACSF2-004 ENSP00000425964 ENST00000504392	E9PF16 [Direct mapping] Acyl-CoA synthetase family member 2, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	572 aa 63.7 kDa	No	1
ACSF2-005 ENSP00000421884 ENST00000502667	Q96CM8 [Direct mapping] Acyl-CoA synthetase family member 2, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005759 [mitochondrial matrix] GO:0006631 [fatty acid metabolic process] GO:0008152 [metabolic process] GO:0016874 [ligase activity] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	602 aa 66.8 kDa	No	1
ACSF2-010 ENSP00000424842 ENST00000506582	D6RF87 [Direct mapping] Acyl-CoA synthetase family member 2, mitochondrial Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	183 aa 19.4 kDa	Yes	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.