Expression of PRR15L in cancer - Summary - The Human Protein Atlas

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PRR15L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRR15L
Gene description	Proline rich 15-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HaCaT, MCF7, SCLC-21H, SK-BR-3, T-47d)
HPA (normal tissue):	Tissue enhanced (duodenum)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA022918
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and stomach cancer (favourable).
Renal cancer p<0.001 Stomach cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA022918

GENE INFORMATION
Gene name	PRR15L (HGNC Symbol)
Synonyms	ATAD4, MGC11242
Description	Proline rich 15-like (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q21.32
Chromosome location (bp)	47951967 - 47957878
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167183 (version 83.38)
Entrez gene	79170
UniProt	Q9BU68 (UniProt - Inferred from homology)
neXtProt	NX_Q9BU68
Antibodypedia	PRR15L antibodies

PROTEIN BROWSER

PRR15L-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRR15L-001 ENSP00000300557 ENST00000300557	Q9BU68 [Direct mapping] Proline-rich protein 15-like protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		103 aa 11.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.