Tissue expression of RAB4B - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RAB4B
Gene description	RAB4B, member RAS oncogene family
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	RAB4B (HGNC Symbol)
Synonyms	FLJ78649, MGC52123
Description	RAB4B, member RAS oncogene family (HGNC Symbol)
Entrez gene summary	RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).[supplied by OMIM, Aug 2009]
Chromosome	19
Cytoband	q13.2
Chromosome location (bp)	40778216 - 40796938
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167578 (version 83.38)
Entrez gene	53916
UniProt	P61018 (UniProt - Evidence at protein level)
neXtProt	NX_P61018
Antibodypedia	RAB4B antibodies

PROTEIN BROWSER

RAB4B-001	RAB4B-003	RAB4B-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAB4B-001 ENSP00000470246 ENST00000594800	P61018 [Direct mapping] Ras-related protein Rab-4B A0A024R0K8 [Target identity:100%; Query identity:100%] HCG1995540, isoform CRA_c; HCG2044074, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0030100 [regulation of endocytosis] GO:0032482 [Rab protein signal transduction] GO:0032593 [insulin-responsive compartment] GO:0046323 [glucose import] GO:0048471 [perinuclear region of cytoplasm] GO:0055037 [recycling endosome] Show all	213 aa 23.6 kDa	No	0
RAB4B-003 ENSP00000471504 ENST00000602173	M0R0X1 [Direct mapping] Ras-related protein Rab-4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0030100 [regulation of endocytosis] GO:0032482 [Rab protein signal transduction] Show all	192 aa 21.2 kDa	No	0
RAB4B-006 ENSP00000349560 ENST00000357052	P61018 [Direct mapping] Ras-related protein Rab-4B A0A024R0K8 [Target identity:100%; Query identity:100%] HCG1995540, isoform CRA_c; HCG2044074, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0030100 [regulation of endocytosis] GO:0032482 [Rab protein signal transduction] GO:0032593 [insulin-responsive compartment] GO:0046323 [glucose import] GO:0048471 [perinuclear region of cytoplasm] GO:0055037 [recycling endosome] Show all	213 aa 23.6 kDa	No	0