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ANKRD33

GENERAL INFORMATION

Gene name

 ANKRD33

Gene description

 Ankyrin repeat domain 33

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Not detected

Protein evidence

 Evidence at transcript level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.

Reliability score

 Uncertain based on 2 antibodies.
HPA040013 , HPA058753
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA040013
HPA058753

GENE INFORMATION

Gene name

 ANKRD33 (HGNC Symbol)

Synonyms

 C12orf7, DKFZp686O1689, PANKY

Description

 Ankyrin repeat domain 33 (HGNC Symbol)

Entrez gene summary

Chromosome

 12

Cytoband

 q13.13

Chromosome location (bp)

 51887960 - 51891664

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000167612 (version 83.38)

Entrez gene

 341405

UniProt

 Q7Z3H0 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q7Z3H0

Antibodypedia

 ANKRD33 antibodies

PROTEIN BROWSER
ANKRD33-001
ANKRD33-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ANKRD33-001
ENSP00000301190
ENST00000301190
Q7Z3H0 [Direct mapping]
Ankyrin repeat domain-containing protein 33
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   THUMBUP predicted membrane proteins
Predicted intracellular proteins
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0035914 [skeletal muscle cell differentiation]
GO:2000678 [negative regulation of transcription regulatory region DNA binding]
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 452 aa
49.4 kDa 		No 0
ANKRD33-005
ENSP00000344690
ENST00000340970
Q7Z3H0 [Direct mapping]
Ankyrin repeat domain-containing protein 33
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   THUMBUP predicted membrane proteins
Predicted intracellular proteins
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:2000678 [negative regulation of transcription regulatory region DNA binding]
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 272 aa
29 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.