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ATCAY

GENERAL INFORMATION

Gene name

 ATCAY

Gene description

 Ataxia, cerebellar, Cayman type

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (cerebral cortex)
GTEx:Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus, pituitary gland)
FANTOM5:Group enriched (brain, caudate, cerebellum, hippocampus, pituitary gland)

Protein evidence

 Evidence at protein level

Protein expression

 Selective expression in CNS.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA017755
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus, pituitary gland)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (brain, caudate, cerebellum, hippocampus, pituitary gland)

GENE INFORMATION

Gene name

 ATCAY (HGNC Symbol)

Synonyms

 BNIP-H

Description

 Ataxia, cerebellar, Cayman type (HGNC Symbol)

Entrez gene summary

 This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008]

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 3879864 - 3928079

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167654 (version 83.38)

Entrez gene

 85300

UniProt

 Q86WG3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86WG3

Antibodypedia

 ATCAY antibodies

PROTEIN BROWSER
ATCAY-001
ATCAY-004
ATCAY-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ATCAY-001
ENSP00000390941
ENST00000450849
Q86WG3 [Direct mapping]
Caytaxin
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0006810 [transport]
GO:0006915 [apoptotic process]
GO:0019894 [kinesin binding]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0031175 [neuron projection development]
GO:0031966 [mitochondrial membrane]
GO:0032880 [regulation of protein localization]
GO:0043005 [neuron projection]
GO:0045202 [synapse]
GO:0048311 [mitochondrion distribution]
GO:0050699 [WW domain binding]
GO:2000212 [negative regulation of glutamate metabolic process]
Show all
 371 aa
42.1 kDa 		No 0
ATCAY-004
ENSP00000470842
ENST00000600960
Q86WG3 [Direct mapping]
Caytaxin
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted intracellular proteins
Disease related genes
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0006810 [transport]
GO:0006915 [apoptotic process]
GO:0019894 [kinesin binding]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0031175 [neuron projection development]
GO:0031966 [mitochondrial membrane]
GO:0032880 [regulation of protein localization]
GO:0043005 [neuron projection]
GO:0045202 [synapse]
GO:0048311 [mitochondrion distribution]
GO:2000212 [negative regulation of glutamate metabolic process]
Show all
 377 aa
42.8 kDa 		No 0
ATCAY-005
ENSP00000471731
ENST00000598136
M0R197 [Direct mapping]
Caytaxin
Show all
Predicted intracellular proteins
Show all
GO:0006915 [apoptotic process]
Show all
 99 aa
11 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.