Expression of GLOD4 in cancer - Summary - The Human Protein Atlas

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GLOD4

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GLOD4
Gene description	Glyoxalase domain containing 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 3 antibodies. HPA021623 , HPA023246 , HPA023248
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA021623	HPA023246	HPA023248

GENE INFORMATION
Gene name	GLOD4 (HGNC Symbol)
Synonyms	C17orf25, CGI-150, HC71
Description	Glyoxalase domain containing 4 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.3
Chromosome location (bp)	757097 - 783390
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167699 (version 83.38)
Entrez gene	51031
UniProt	Q9HC38 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HC38
Antibodypedia	GLOD4 antibodies

PROTEIN BROWSER

GLOD4-001	GLOD4-005	GLOD4-007	GLOD4-008	GLOD4-201	GLOD4-202	GLOD4-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GLOD4-001 ENSP00000301329 ENST00000301329	Q9HC38 [Direct mapping] Glyoxalase domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0070062 [extracellular exosome] Show all	298 aa 33.2 kDa	No	0
GLOD4-005 ENSP00000301328 ENST00000301328	Q9HC38 [Direct mapping] Glyoxalase domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0070062 [extracellular exosome] Show all	313 aa 34.8 kDa	No	0
GLOD4-007 ENSP00000458849 ENST00000573137	I3L1I0 [Direct mapping] Glyoxalase domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		115 aa 12.7 kDa	No	0
GLOD4-008 ENSP00000460634 ENST00000576419	I3L3Q4 [Direct mapping] Glyoxalase domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		227 aa 25.5 kDa	No	0
GLOD4-201 ENSP00000444315 ENST00000536578	F6TLX2 [Direct mapping] Glyoxalase domain-containing protein 4 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		502 aa 54.7 kDa	No	0
GLOD4-202 ENSP00000486778 ENST00000625892	I3NI24 [Direct mapping] Glyoxalase domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		36 aa 4.2 kDa	No	0
GLOD4-203 ENSP00000486254 ENST00000628529	I3NI27 [Direct mapping] Glyoxalase domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		36 aa 4.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.