Expression of NUDT16L1 in cancer - Summary - The Human Protein Atlas

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NUDT16L1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	NUDT16L1
Gene description	Nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression with a granular pattern.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA044186 , HPA063605
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and lung cancer (favourable).
Renal cancer p<0.001 Lung cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044186	HPA063605

GENE INFORMATION
Gene name	NUDT16L1 (HGNC Symbol)
Synonyms	SDOS
Description	Nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	4693694 - 4695859
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168101 (version 83.38)
Entrez gene	84309
UniProt	Q9BRJ7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BRJ7
Antibodypedia	NUDT16L1 antibodies

PROTEIN BROWSER

NUDT16L1-001	NUDT16L1-002	NUDT16L1-003	NUDT16L1-004	NUDT16L1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NUDT16L1-001 ENSP00000306670 ENST00000304301	Q9BRJ7 [Direct mapping] Protein syndesmos Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] GO:0030515 [snoRNA binding] GO:0044822 [poly(A) RNA binding] Show all	211 aa 23.3 kDa	No	0
NUDT16L1-002 ENSP00000458144 ENST00000405142	Q9BRJ7 [Direct mapping] Protein syndesmos Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] GO:0030515 [snoRNA binding] GO:0044822 [poly(A) RNA binding] Show all	247 aa 26 kDa	No	0
NUDT16L1-003 ENSP00000468346 ENST00000586536	W4VSQ8 [Direct mapping] Nudix (Nucleoside diphosphate linked moiety X)-type motif 16-like 1, isoform CRA_b; Protein syndesmos Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	192 aa 21 kDa	No	0
NUDT16L1-004 ENSP00000466854 ENST00000586252	K7ENA3 [Direct mapping] Protein syndesmos Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	171 aa 18.9 kDa	No	0
NUDT16L1-005 ENSP00000464821 ENST00000590460	K7EIN2 [Direct mapping] Protein syndesmos Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	198 aa 21.8 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.