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Moderate to strong nuclear positivity was observed in most malignancies. Several cases of malignant lymphomas and melanomas as well as prostate and testicular cancers were weakly stained or negative.
GENE INFORMATION
Gene name
IRF2BP2 (HGNC Symbol)
Synonyms
IRF-2BP2
Description
Interferon regulatory factor 2 binding protein 2 (HGNC Symbol)
Entrez gene summary
This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]