Expression of FAM107A in cancer - Summary - The Human Protein Atlas

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FAM107A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM107A
Gene description	Family with sequence similarity 107, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (glioma)
HPA (cell line):	Cell line enriched (HUVEC TERT2)
HPA (normal tissue):	Group enriched (cerebral cortex, fallopian tube)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Expression mainly in the CNS.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining in cells/structures not annotated, view images. Pending external verification. Pending additional tissues.
Reliability score	Approved based on 1 antibody. HPA055888
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (favourable) and endometrial cancer (unfavourable).
Liver cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA055888

GENE INFORMATION
Gene name	FAM107A (HGNC Symbol)
Synonyms	DRR1, TU3A
Description	Family with sequence similarity 107, member A (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband
Chromosome location (bp)	58564117 - 58627610
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168309 (version 83.38)
Entrez gene	11170
UniProt	O95990 (UniProt - Evidence at protein level)
neXtProt	NX_O95990
Antibodypedia	FAM107A antibodies

PROTEIN BROWSER

FAM107A-001	FAM107A-002	FAM107A-003	FAM107A-004	FAM107A-005	FAM107A-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM107A-001 ENSP00000419124 ENST00000474531	O95990 [Direct mapping] Protein FAM107A A0A024R327 [Target identity:100%; Query identity:100%] Family with sequence similarity 107, member A, isoform CRA_c Show all	Predicted intracellular proteins Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	175 aa 20.9 kDa	No	0
FAM107A-002 ENSP00000354270 ENST00000360997	O95990 [Direct mapping] Protein FAM107A Q6IAM1 [Target identity:100%; Query identity:100%] Family with sequence similarity 107 member A transcript variant; Family with sequence similarity 107, member A, isoform CRA_a; TU3A protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	144 aa 17.5 kDa	No	0
FAM107A-003 ENSP00000400858 ENST00000447756	O95990 [Direct mapping] Protein FAM107A Show all	Predicted intracellular proteins Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	172 aa 20.5 kDa	No	0
FAM107A-004 ENSP00000377991 ENST00000394481	O95990 [Direct mapping] Protein FAM107A Q6IAM1 [Target identity:100%; Query identity:100%] Family with sequence similarity 107 member A transcript variant; Family with sequence similarity 107, member A, isoform CRA_a; TU3A protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	144 aa 17.5 kDa	No	0
FAM107A-005 ENSP00000419529 ENST00000464064	O95990 [Direct mapping] Protein FAM107A Show all	Predicted intracellular proteins Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	135 aa 15.9 kDa	No	0
FAM107A-007 ENSP00000418038 ENST00000465970	C9JAU5 [Direct mapping] Protein FAM107A Show all	Predicted intracellular proteins Show all		105 aa 12.8 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.