Tissue expression of ADAM29 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ADAM29
Gene description	ADAM metallopeptidase domain 29
Protein class	Disease related genes Enzymes Potential drug targets Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	ADAM29 (HGNC Symbol)
Synonyms	CT73, svph1
Description	ADAM metallopeptidase domain 29 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	q34.1
Chromosome location (bp)	174829668 - 174978180
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168594 (version 83.38)
Entrez gene	11086
UniProt	Q9UKF5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UKF5
Antibodypedia	ADAM29 antibodies

PROTEIN BROWSER

ADAM29-001	ADAM29-002	ADAM29-004	ADAM29-005	ADAM29-006	ADAM29-201	ADAM29-202	ADAM29-203	ADAM29-204

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADAM29-001 ENSP00000384229 ENST00000404450	Q9UKF5 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	Enzymes Peptidases Metallopeptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0004222 [metalloendopeptidase activity] GO:0005887 [integral component of plasma membrane] GO:0006508 [proteolysis] GO:0007283 [spermatogenesis] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] Show all	820 aa 92.8 kDa	Yes	1
ADAM29-002 ENSP00000423517 ENST00000514159	Q9UKF5 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	Enzymes Peptidases Metallopeptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0004222 [metalloendopeptidase activity] GO:0005887 [integral component of plasma membrane] GO:0006508 [proteolysis] GO:0007283 [spermatogenesis] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] Show all	820 aa 92.8 kDa	Yes	1
ADAM29-004 ENSP00000427370 ENST00000505141	D6RIU9 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		14 aa 1.6 kDa	No	0
ADAM29-005 ENSP00000427674 ENST00000502940	D6RHU0 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004222 [metalloendopeptidase activity] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	90 aa 10.1 kDa	Yes	0
ADAM29-006 ENSP00000422537 ENST00000502305	D6RBU0 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		44 aa 4.9 kDa	Yes	0
ADAM29-201 ENSP00000352177 ENST00000359240	Q9UKF5 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	Enzymes Peptidases Metallopeptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0004222 [metalloendopeptidase activity] GO:0005887 [integral component of plasma membrane] GO:0006508 [proteolysis] GO:0007283 [spermatogenesis] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] Show all	820 aa 92.8 kDa	Yes	1
ADAM29-202 ENSP00000414544 ENST00000445694	Q9UKF5 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	Enzymes Peptidases Metallopeptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0004222 [metalloendopeptidase activity] GO:0005887 [integral component of plasma membrane] GO:0006508 [proteolysis] GO:0007283 [spermatogenesis] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] Show all	820 aa 92.8 kDa	Yes	1
ADAM29-203 ENSP00000484862 ENST00000615367	Q9UKF5 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	Enzymes Peptidases Metallopeptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0004222 [metalloendopeptidase activity] GO:0005887 [integral component of plasma membrane] GO:0006508 [proteolysis] GO:0007283 [spermatogenesis] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] Show all	820 aa 92.8 kDa	Yes	1
ADAM29-204 ENSP00000478469 ENST00000618444	Q9UKF5 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 29 Show all	Enzymes Peptidases Metallopeptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0004222 [metalloendopeptidase activity] GO:0005887 [integral component of plasma membrane] GO:0006508 [proteolysis] GO:0007283 [spermatogenesis] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] Show all	820 aa 92.8 kDa	Yes	1