Expression of ABHD15 in cancer - Summary - The Human Protein Atlas

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ABHD15

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABHD15
Gene description	Abhydrolase domain containing 15
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA014470
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA014470

GENE INFORMATION
Gene name	ABHD15
Synonyms
Description	Abhydrolase domain containing 15 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q11.2
Chromosome location (bp)	29560547 - 29567137
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168792 (version 83.38)
Entrez gene	116236
UniProt	Q6UXT9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6UXT9
Antibodypedia	ABHD15 antibodies

PROTEIN BROWSER

ABHD15-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD15-001 ENSP00000302657 ENST00000307201	Q6UXT9 [Direct mapping] Abhydrolase domain-containing protein 15 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016787 [hydrolase activity] Show all	468 aa 51.8 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.