Fields »
ABOUT
HELP
BLOG
DDX19A

GENERAL INFORMATION

Gene name

 DDX19A

Gene description

 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A

Protein class

 Enzymes
Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic and nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA045252
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and head and neck cancer (unfavourable).
Liver cancer p<0.001
Head and neck cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA045252

GENE INFORMATION

Gene name

 DDX19A (HGNC Symbol)

Synonyms

 DDX19L, FLJ11126

Description

 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A (HGNC Symbol)

Entrez gene summary

Chromosome

 16

Cytoband

 q22.1

Chromosome location (bp)

 70346829 - 70373383

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000168872 (version 83.38)

Entrez gene

 55308

UniProt

 Q9NUU7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NUU7

Antibodypedia

 DDX19A antibodies

PROTEIN BROWSER
DDX19A-001
DDX19A-004
DDX19A-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DDX19A-001
ENSP00000306117
ENST00000302243
Q9NUU7 [Direct mapping]
ATP-dependent RNA helicase DDX19A
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0004004 [ATP-dependent RNA helicase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005643 [nuclear pore]
GO:0005737 [cytoplasm]
GO:0006406 [mRNA export from nucleus]
GO:0008150 [biological_process]
GO:0010501 [RNA secondary structure unwinding]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0031965 [nuclear membrane]
Show all
 478 aa
54 kDa 		No 0
DDX19A-004
ENSP00000410243
ENST00000417604
I3L0H8 [Direct mapping]
ATP-dependent RNA helicase DDX19A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0004004 [ATP-dependent RNA helicase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006406 [mRNA export from nucleus]
GO:0010501 [RNA secondary structure unwinding]
Show all
 447 aa
50.5 kDa 		No 0
DDX19A-007
ENSP00000460180
ENST00000575878
I3L352 [Direct mapping]
ATP-dependent RNA helicase DDX19A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0004004 [ATP-dependent RNA helicase activity]
GO:0005524 [ATP binding]
GO:0005622 [intracellular]
GO:0006406 [mRNA export from nucleus]
GO:0010501 [RNA secondary structure unwinding]
Show all
 396 aa
44.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.