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SOX14

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GENERAL INFORMATION

Gene name

 SOX14

Gene description

 SRY (sex determining region Y)-box 14

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Not detected

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 SOX14 (HGNC Symbol)

Synonyms

 SOX28

Description

 SRY (sex determining region Y)-box 14 (HGNC Symbol)

Entrez gene summary

 This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome. [provided by RefSeq, Jul 2008]

Chromosome

 3

Cytoband

 q22.3

Chromosome location (bp)

 137764284 - 137766338

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000168875 (version 83.38)

Entrez gene

 8403

UniProt

 O95416 (UniProt - Evidence at protein level)

neXtProt

 NX_O95416

Antibodypedia

 SOX14 antibodies

PROTEIN BROWSER
SOX14-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SOX14-001
ENSP00000305343
ENST00000306087
O95416 [Direct mapping]
Transcription factor SOX-14
Show all
Predicted intracellular proteins
Transcription factors
   Other all-alpha-helical DNA-binding domains
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003682 [chromatin binding]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007399 [nervous system development]
GO:0007601 [visual perception]
GO:0009649 [entrainment of circadian clock]
GO:0043565 [sequence-specific DNA binding]
GO:0044798 [nuclear transcription factor complex]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046982 [protein heterodimerization activity]
GO:2001222 [regulation of neuron migration]
Show all
 240 aa
26.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.