Tissue expression of CTRB2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CTRB2
Gene description	Chymotrypsinogen B2
Protein class	Enzymes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (pancreas)
GTEx:	Tissue enriched (pancreas)
FANTOM5:	Tissue enriched (pancreas)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (pancreas)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (pancreas)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (pancreas)

GENE INFORMATION
Gene name	CTRB2
Synonyms
Description	Chymotrypsinogen B2 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q23.1
Chromosome location (bp)	75204096 - 75207185
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168928 (version 83.38)
Entrez gene	440387
UniProt	Q6GPI1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6GPI1
Antibodypedia	CTRB2 antibodies

PROTEIN BROWSER

CTRB2-001	CTRB2-004	CTRB2-005	CTRB2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CTRB2-001 ENSP00000303963 ENST00000303037	Q6GPI1 [Direct mapping] Chymotrypsinogen B2 Chymotrypsin B2 chain A Chymotrypsin B2 chain B Chymotrypsin B2 chain C Show all	Enzymes ENZYME proteins Hydrolases Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0007586 [digestion] GO:0009235 [cobalamin metabolic process] GO:0022617 [extracellular matrix disassembly] GO:0030198 [extracellular matrix organization] GO:0044281 [small molecule metabolic process] Show all	263 aa 27.9 kDa	Yes	0
CTRB2-004 ENSP00000457279 ENST00000567767	H3BTQ4 [Direct mapping] Chymotrypsinogen B2 Show all	Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0006508 [proteolysis] Show all	114 aa 12.2 kDa	No	0
CTRB2-005 ENSP00000455207 ENST00000562387	H3BP92 [Direct mapping] Chymotrypsinogen B2 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0006508 [proteolysis] Show all	137 aa 14.7 kDa	No	0
CTRB2-006 ENSP00000454599 ENST00000562106	H3BMY1 [Direct mapping] Chymotrypsinogen B2 Show all	Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0006508 [proteolysis] Show all	168 aa 18 kDa	No	0