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ATP5I

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GENERAL INFORMATION

Gene name

 ATP5I

Gene description

 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the mitochondria.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Mitochondria (validated)

DATA RELIABILITY

Reliability score

 Validated based on 1 antibody.
HPA035010
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the mitochondria.

Main location

 Mitochondria (validated)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA035010 A-431 Mitochondria
HPA035010 U-2 OS Mitochondria
HPA035010 U-251 MG Mitochondria

GENE INFORMATION

Gene name

 ATP5I

Synonyms

Description

 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E (HGNC Symbol)

Entrez gene summary

 Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]

Chromosome

 4

Cytoband

 p16.3

Chromosome location (bp)

 672436 - 674338

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000169020 (version 83.38)

Entrez gene

 521

UniProt

 P56385 (UniProt - Evidence at protein level)

neXtProt

 NX_P56385

Antibodypedia

 ATP5I antibodies

PROTEIN BROWSER
ATP5I-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ATP5I-001
ENSP00000306003
ENST00000304312
P56385 [Direct mapping]
ATP synthase subunit e, mitochondrial ATP synthase subunit e, mitochondrial, N-terminally processed
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   Phobius predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000276 [mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005753 [mitochondrial proton-transporting ATP synthase complex]
GO:0015078 [hydrogen ion transmembrane transporter activity]
GO:0015986 [ATP synthesis coupled proton transport]
GO:0016887 [ATPase activity]
GO:0022857 [transmembrane transporter activity]
GO:0022904 [respiratory electron transport chain]
GO:0042776 [mitochondrial ATP synthesis coupled proton transport]
GO:0044237 [cellular metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046034 [ATP metabolic process]
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 69 aa
7.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.