Expression of ACTBL2 in cancer - Summary - The Human Protein Atlas

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ACTBL2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ACTBL2
Gene description	Actin, beta-like 2
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (RPTEC TERT1, SiHa, U-2 OS)
HPA (normal tissue):	Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 2 antibodies. HPA041264 , HPA041271
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041264	HPA041271

GENE INFORMATION
Gene name	ACTBL2 (HGNC Symbol)
Synonyms	DKFZp686D0972
Description	Actin, beta-like 2 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q11.2
Chromosome location (bp)	57480016 - 57482809
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169067 (version 83.38)
Entrez gene	345651
UniProt	Q562R1 (UniProt - Evidence at protein level)
neXtProt	NX_Q562R1
Antibodypedia	ACTBL2 antibodies

PROTEIN BROWSER

ACTBL2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACTBL2-001 ENSP00000416706 ENST00000423391	Q562R1 [Direct mapping] Beta-actin-like protein 2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005524 [ATP binding] GO:0005615 [extracellular space] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] GO:0008150 [biological_process] GO:0070062 [extracellular exosome] Show all	376 aa 42 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.